Severe Vulvovaginal Candidiasis.

Recurrent VVC is defined as four or more episodes of symptomatic VVC annually. Non-albicans Candida kind are found in 10% to 20% of persons with recurrent VVC, so vaginal cultures should be obtained to confirm non-albicans sort that are not as responsive to conventional therapies. Although each occurrence of recurrent VVC may respond to a piece of ground length therapy of oral or topical agents, experts recommend a longer continuance of initial therapy such as 7 to 14 days of topical therapy or 150 mg oral fluconazole (Diflucan) administered once and repeated 3 days later for a quantity of two doses. A reparation regimen for 6 months has shown to be effective, but 30% to 40% of persons will have recurrent disease once wrongful conduct therapy is discontinued. The recommended 6-month keep regimens include clotrimazole (Gyne-Lotrimin) 500 mg vaginal suppositories once weekly; ketoconazole (Nizoral) 100 mg once daily; fluconazole (Diflucan) 100 to 150 mg once weekly; and itraconazole(Sporanox) 400 mg once monthly or 100 mg once daily.


Severe VVC is characterized by extensive vulvar erythema, edema, denunciation, and cleft shaping. Persons with severe VCC have insufficient responses to tract courses of either topical or oral therapy. The recommended communicating is either 7 to 14 days of topical azole or 150 mg fluconazole (Diflucan) in two sequential doses (with the unit of time dose 72 period of time after the initial dose).Non-albicans Vulvovaginal Candidiasis.